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Thread: Stilul de viata modern si medicina actuala

  1. Back To Top | #61
    Intuitive Investigator Benvolio's Avatar
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    Nov 2002
    bogdan george, good point. Am cautat studiul cu pricina - cred ca e asta:

    Heritability of life span in the Old Order Amish. - PubMed - NCBI

    Although a familial contribution to human longevity is recognized, the nature of this contribution is largely unknown. We have examined the familial contribution to life span in the Old Order Amish (OOA) population of Lancaster County, Pennsylvania. Analyses were conducted on 1,655 individuals, representing all those born prior to 1890 and appearing in the most widely available genealogy, surviving until at least age 30 years, and with known date of death. Mean age at death (+/-SD) in this population was 70.7 +/- 15.6 years, and this did not change appreciably over time. Parental and offspring ages at death were significantly correlated, as were ages of death among siblings. Offspring longevity was correlated with longevity of both parents, and in more or less additive fashion. For example, mean offspring age at death was 69.4 +/- 15.3 years in individuals for whom both parents died before the age of 75 years (n = 280) and increased to 73.5 +/- 16.0 years in individuals for whom neither parent died before the age of 75 years (n = 311). These differences were highly significant (P = 0.006). We estimated heritability of life span to be 25% +/- 5%, suggesting that the additive effects of genes account for one quarter of the total variability in life span in the OOA. We conclude that longevity is moderately heritable in the OOA, that the genetic effects are additive, and that genetic influences on longevity are likely to be expressed across a broad range of ages. Published 2001 Wiley-Liss, Inc.
    Deci daca bine inteleg, Amishii care ajungeau la 30 traiau pana la 70 in medie - 70 nu era speranta de viata medie pentru toata populatia Amish, cum intelesese jurnalistul citat de mine.

    limelight, la ce te referi, la epigenetics ? Daca da, se poate transmite, dar pe termen scurt.

    Pe undeva ai tu dreptate cu stilul de viata - se pare ca Amishii au semnificativ mai putin cancer (in special din cel dat de fumat):

    The study of Amish suggests that clean living can lead to healthier life. Overall cancer rates in this population were 60 percent of the age-adjusted rate for Ohio and 56 percent of the national rate. The incidence of tobacco-related cancers in the Amish adults was 37 percent of the rate for Ohio adults, and the incidence of non-tobacco-related cancer was 72 percent.

    “The Amish are at an increased risk for a number of genetic disorders but they probably have protection against many types of cancer both through their lifestyle – there is very little tobacco or alcohol use and limited sexual partners – and through genes that may reduce their susceptibility to cancer,” said Westman, who co-authored the study with OSUCCC-James researcher Amy K. Ferketich, who specializes in epidemiology.

    The findings were reported in a recent issue of the journal Cancer Causes & Control. The study, which spanned 1996-2003 and is the first of its kind, looked at the incidence of 24 types of cancer in the Amish population. Of the 24 types of cancer studied, the incidence of seven of them – cervical, laryngeal, lung, oral cavity/pharyngeal, melanoma, breast and prostate – was low enough compared with the Ohio rate to be statistically significant.
    Amish Have Lower Rates Of Cancer, Ohio State Study Shows - Division of Human Genetics

    si mult mai putina obezitate - desi au acceasi predispozitie ca restul albilor - pt ca fac mult mai mult efort fizic:

    One recent study of the Amish, published in the official scientific journal of the American College of Sports Medicine (the largest sports medicine and exercise organization in the world), provides enormous insight into the relationship between high amounts of work-related physical activity and obesity. The study was designed to use the Amish, known for their physically demanding hard working lifestyle and living without modern technology, to determine how technology influences physical activity levels in modern society. Pedometers were placed on a large group of Amish farmers and their physical activities were logged for 7 days. Amish men recorded an average of 18,425 steps a day, Amish women logged 14,196 daily steps. By most standards 10,000 steps per day is required to be considered to live a "very active lifestyle". Other forms of physical activity were also measured and the findings were that the Amish performed 6 times more physical activity per day than a study of 2,000 participants in 12 modernized nations. Only 4% of the Amish population are obese as defined by a Body Mass Index above 30, whereas 31% of the US adult population is obese.

    Pe de alta parte, din cauza consangvinizarii, comunitatii inchise, au boli genetice specifice, foarte rare la restul lumii. Si cand au probleme serioase de sanatate, merg la doctor.

    Cred ca toti suntem de acord ca sedentarismul / fumatul / poluarea aerului dauneaza - partea dubioasa e aia cum ca medicina actuala / medicamentele mai mult dauneaza.
    Last edited by Benvolio; 25-11-2017 at 10:16. Reason: clarificare
    "Viata e complexa si are multe aspecte." (©Filantropica)

  2. Back To Top | #62
    Intuitive Investigator Benvolio's Avatar
    Join Date
    Nov 2002
    Longevity among hunter-gatherers: a cross-cultural examination

    Among traditional hunter-gatherers, the average life expectancy at birth varies from 21 to 37 years, the proportion surviving to age 45 varies between 26 percent and 43 percent, and life expectancy at age 45 varies from 14 to 24 years.
    Deci la "salbaticii" din zilele noastre, doar intre un sfert si sub jumatate nu mor de tineri ci ajung la 45 de ani - si aceia traiesc in medie undeva intre 59 - 69 de ani (astea variaza de la trib la trib).

    Nu mi se par de invidiat.

    Iar la oamenii (si Neanderthalii) preistorici dinainte de raspandirea agriculturii se pare ca era chiar mai rau ca la triburile primitive din zilele noastre:

    Late Pleistocene adult mortality patterns and modern human establishment

    The establishment of modern humans in the Late Pleistocene, subsequent to their emergence in eastern Africa, is likely to have involved substantial population increases, during their initial dispersal across southern Asia and their subsequent expansions throughout Africa and into more northern Eurasia. An assessment of younger (20–40 y) versus older (>40 y) adult mortality distributions for late archaic humans (principally Neandertals) and two samples of early modern humans (Middle Paleolithic and earlier Upper Paleolithic) provides little difference across the samples. All three Late Pleistocene samples have a dearth of older individuals compared with Holocene ethnographic/historical samples. They also lack older adults compared with Holocene paleodemographic profiles that have been critiqued for having too few older individuals for subsistence, social, and demographic viability. Although biased, probably through a combination of preservation, age assessment, and especially Pleistocene mobility requirements, these adult mortality distributions suggest low life expectancy and demographic instability across these Late Pleistocene human groups. They indicate only subtle and paleontologically invisible changes in human paleodemographics with the establishment of modern humans; they provide no support for a life history advantage among early modern humans.
    Last edited by Benvolio; 07-12-2017 at 10:32. Reason: inca un studiu - despre longevitatea din preistorie
    "Viata e complexa si are multe aspecte." (©Filantropica)

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